Vaccination and allergies: what do we know? A little

One of the strongest adverse reactions that can occur due to covid-19 is anaphylaxis, that is, a general and widespread allergic reaction.

Since COVID-19 vaccines are new, there are many unknown factors. For example, it is not known whether an individual will develop an allergy or severe anaphylaxis after being vaccinated. It is also very difficult to understand whether people with certain allergies can be vaccinated. This is because subjects with a history of allergy were excluded in clinical trials. To date, a limited number of studies are available evaluating the safety of COVID-19 vaccines in individuals with a history of allergies.

Scientists then sought to fill the gap in research regarding adverse reactions to Pfizer's COVID-19 vaccine among individuals with allergies. They have published their results on the medRxiv * prepress server. The current study was conducted at Yamagata University Hospital, Japan, where the BNT162b2 mRNA COVID-19 vaccine was administered to hospital staff and medical students between March 3, 2021 and August 27, 2021.

The researchers obtained responses from 1,586 participants after the first vaccination and 1306 participants after the second dose of the BNT162b2 vaccine, the Pfizer vaccine. After analyzing the data, the scientists revealed that some common adverse reactions such as pain and swelling at the vaccination site, fever, fatigue, headache, nausea, chills, arthralgia and muscle pain outside the vaccination site prevailed. Typically, the frequency and severity of the most adverse reactions occurred after the second vaccination dose compared to the first. Furthermore, it is interesting to note that this study revealed that women and younger individuals experienced adverse reactions at a higher rate than males and the elderly.

The present study reported that subjects with a history of allergies experienced some adverse reactions of greater severity and the duration of symptoms lasted for a longer period than subjects without allergies. This finding agrees with a previous study that reported that COVID-19 vaccination of hospital staff showed a higher frequency of adverse reactions in the presence of allergy.

Even if there were no particularly serious cases, this study shows how the interaction between the vaccine and other pathological situations: after all, the vaccine seems to solve everything, so why understand how it works?

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The article Vaccination and allergies: what do we know? Little comes from .

This is a machine translation of a post published on Scenari Economici at the URL on Fri, 24 Sep 2021 20:57:55 +0000.