Big study reveals two adverse events to the Covid vaccine not previously identified
Two new but rare side effects of the Covid-19 vaccine – a neurological disorder and inflammation of the spinal cord – have been detected by researchers in the largest vaccine safety study conducted so far, as reported in a mainstream newspaper, the Guardian
The study, conducted on over 99 million people from Australia, Argentina, Canada, Denmark, Finland, France, New Zealand and Scotland. Of course, the paper reported, the research confirmed the rarity of known vaccine complications, and researchers confirmed that the benefits of the Covid-19 vaccine continue to “largely outweigh the risks.”
Researchers working as part of the Global Vaccine Data Network used deidentified electronic health data to compare the rates of 13 brain, blood and heart conditions in people after they received the Pfizer, Moderna or AstraZeneca vaccine with the rate they would expect of these pathologies in the population before the pandemic.
The study confirmed with a high level of precision the known links between the mRNA vaccines (Pfizer and Moderna) and the rare side effects of myocarditis (inflammation of the heart muscle) and pericarditis (swelling of the thin sac covering the heart). It also confirmed Guillain-Barré syndrome (in which the immune system attacks the nerves) and cerebral venous sinus thrombosis (a type of blood clot in the brain) as rare side effects linked to the AstraZeneca vaccine.
But a new rare side effect was also identified in the data analysis, acute disseminated encephalomyelitis, an inflammation and swelling of the brain and spinal cord, linked to the AstraZeneca vaccine.
The results were published on Friday in the International Journal of Vaccine , and it is interesting to note that the journal is becoming a monograph on the study of the side effects of Covid vaccines.
Prof. Jim Buttery, co-director of the Global Vaccine Data Network, said the discovery prompted researchers to independently confirm the side effect by completing a second study, this time analyzing a separate dataset of 6.8 millions of Australians who have received the AstraZeneca vaccine.
The Australian study not only confirmed that acute disseminated encephalomyelitis is a rare side effect, but the large amount of AstraZeneca-specific data helped identify a second new rare side effect, known as transverse myelitis, or inflammation of the spinal cord.
Published Friday in Vaccine, the Australian study found that the data translates into an extremely low risk of acute disseminated encephalomyelitis, at 0.78 cases per million doses and 1.82 cases per million doses for transverse myelitis. At the same time, these large-scale studies allow the identification of side effects that would otherwise not have been immediately linked to the vaccine itself.
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The article Big study reveals two adverse events to the Covid vaccine not previously identified comes from Scenari Economici .
This is a machine translation of a post published on Scenari Economici at the URL https://scenarieconomici.it/grosso-studio-rivela-due-eventi-avversi-al-vaccino-covid-non-prima-identificati/ on Fri, 23 Feb 2024 09:30:38 +0000.