Pfizer-Biontech, how much the Covid vaccine works on adolescents

31 March 20213 years ago babelfish

All the results of Pfizer-Biontech's Covid-19 vaccine according to a study of 2,260 adolescents aged 12 to 15 years

100% effectiveness in protecting against Covid-19.

These are the better than expected results recorded by the Pfizer-BioNTech vaccine administered experimentally to children aged 12 years or older. This age group could be vaccinated before the next school year. All the details.

EFFECTIVENESS

Let's start with the results. Pfizer-BioNTech vaccine, BNT162b2 , is 100% effective in protecting against Covid, according to a phase 3 study, conducted on adolescents aged 12 to 15 years of age with or without prior evidence of Sars-CoV-2 infection. -19, generating robust antibody responses, “even higher than those previously recorded in vaccinated participants aged between 16 and 25 years and was well tolerated”, the company specifies .

I STUDY

The study enrolled 2,260 teenagers between the ages of 12 and 15 in the United States. In the study, 18 cases of COVID-19 were observed in the placebo group (n = 1,129) compared with none in the vaccinated group (n = 1,131).

STRONG ANTI-BODY RESPONSE

Administration of the vaccine “resulted in the geometric mean of SARS-CoV-2 neutralizing antibody titers (GMTs) of 1,239.5, demonstrating strong immunogenicity in a subset of adolescents one month after the second dose,” explains Pfizer.

VACCINATION BEFORE NEXT SCHOOL YEAR?

Thanks to the good results, the vaccine could be given to children before the start of the next school year. "We share the urgency to expand the authorization of our vaccine for use in younger populations and are encouraged by the data from clinical trials on adolescents aged 12-15," said Albert Bourla, president and chief executive officer. by Pfizer.

“We plan to submit this data to the FDA as a proposed amendment to our Emergency Use Authorization in the coming weeks and to other regulators around the world, with the hope of starting vaccinating this age group before the start of the next school year, ”he added.

THE STUDY ON CHILDREN 6 MONTHS-12 YEARS

Pfizer and BionTech are also moving towards administration to children aged 6 months to 12 years. In recent days, the enrollment of children has begun for the launch of a global phase 1/2/3 study to further evaluate the safety, tolerability and immunogenicity of the Pfizer-BioNTech COVID-19 vaccine.

This is a machine translation from Italian language of a post published on Start Magazine at the URL https://www.startmag.it/sanita/pfizer-biontech-quanto-funziona-il-vaccino-anti-covid-sugli-adolescenti/ on Wed, 31 Mar 2021 14:48:55 +0000.