Pfizer, Moderna, Astrazeneca and Janssen: how effective are Covid vaccines?
A monitoring of the vaccinated confirms the high efficacy of Pfizer-Biontech vaccines. Confirmations on high efficacy also for Moderna. All the details on the data of the houses
The Pfizer-BioNTech vaccine is up to 91.3% effective in preventing Covid-19. This is confirmed by the monitoring of the vaccinated volunteers at an advanced stage.
The other mRna vaccine, Moderna's, has also been shown to have very high efficacy in preventing coronavirus.
The effectiveness of Astrazeneca, confirmed in the leaflet revised by the EMA, remains below 60%.
THE RESULTS OF PFIZER
According to the results announced by Pfizer-Biontech, the Covid-19 vaccine has a vaccine efficacy of 91.3%, from seven days to six months after the second dose. The drug, on the other hand, is 100% effective in preventing serious illness, as defined by the US Centers for Disease Control and Prevention.
EFFECTIVENESS AGAINST THE SOUTH AFRICAN VARIANT
The vaccine also appears to effectively prevent the variant found in South Africa. "The vaccine was 100% effective in preventing COVID-19 cases in South Africa, where the B.1.351 lineage is prevalent , " explains Pfizer.
MONITORING
The results emerged from monitoring 44,000 participants aged 16 and over, with over 12,000 vaccinated participants having a follow-up of at least six months after the second dose.
"These data confirm the favorable efficacy and safety profile of our vaccine and allow us to submit a biologic license application to the US FDA," said Albert Bourla, Pfizer president and chief executive officer. "The high vaccine efficacy observed up to six months after a second dose and against the variant prevalent in South Africa provides further confidence in the overall efficacy of our vaccine."
DATA OF THE CDC
The numbers announced by Pfizer seem to be a confirmation of those that emerged from the monitoring of the CD, on 4,000 patients 13 consecutive weeks after the vaccine.
“In real-world conditions, the mRNA vaccine efficacy of complete immunization (≥14 days after the second dose) was 90% against SARS-CoV-2 infections regardless of symptom status; the efficacy of the partial immunization vaccine (≥14 days after the first dose but before the second dose) was 80%, ” writes the American CDC.
THE EFFECTIVENESS OF ASTRAZENECA
The effectiveness of the anti Covid-19 vaccine from Astrazeneca, of which Ema has revised the leaflet for the change of name (in “Vaxzevria”) and of the contraindications (added risk of thrombosis), remains always below the threshold of 60%. The vaccine is 59.5% effective, based on "a pooled analysis of two ongoing randomized, blinded, controlled clinical trials: a Phase II / III study, COV002, in adults aged ≥18. years (including the elderly) in the UK, and a phase III study, COV003, in adults aged ≥18 years (including the elderly) in Brazil ", reads the updated leaflet, despite a study conducted in America, according to the data from the Anglo-Swedish company, showed that the vaccine is 79% effective.
JANSSEN'S VACCINE
Janssen's drug, which is expected to arrive in Italy on April 16, results in "a 67% reduction in the number of symptomatic COVID-19 cases after 2 weeks in people who have received the Covid-19 vaccine".
This is a machine translation from Italian language of a post published on Start Magazine at the URL https://www.startmag.it/sanita/pfizer-moderna-astrazeneca-e-janssen-quanto-sono-efficaci-i-vaccini-anti-covid/ on Sun, 04 Apr 2021 15:40:53 +0000.