How effective is the Sputnik V vaccine against Omicron?
The Spallanzani Institute in Rome conducted a study on the efficacy of the Sputnik V vaccine against Omicron. Here are the results and comparisons with Pfizer
There is an Italian-Russian cooperation behind a comparative study on the effectiveness of Sputnik V against the Omicron variant, which is believed to be very resistant to available vaccines. The Lazzaro Spallanzani Research Institute in Rome, together with the Gamaleya Institute in Moscow, announced the results on the protection offered by the Russian vaccine. And they are better than those seen with Pfizer. Will it be Sputnik V's revenge ?
RESULTS OF THE STUDY
“All licensed vaccines significantly lose activity against Omicron. The results of the experiments, conducted in collaboration between the Spallanzani Institute and the Gamaleya Institute, have documented that over 70% of the people vaccinated with Sputnik V maintain a neutralizing activity against Omicron, and this activity is largely maintained even after 3- 6 months from vaccination ".
This is what we read in a scientific article in preprint published on medRxiv signed by the 12 scientists of Spallanzani and 9 Russians, led by Professor Francesco Vaia, director of Spallanzani, and by Alexander Gintsburg, director of Gamaleya.
SPUTNIK V VS PFIZER
"The Coronavirus Sputnik vaccine demonstrates titers of virus neutralizing antibodies to the Omicron variant (B.1.1.529) more than 2 times higher than 2 doses of Pfizer vaccine (2.1 times higher in total and 2.6 times higher 3 months after vaccination), ”said the Russian sovereign wealth fund RDFI , responsible for marketing and investor of Sputnik V.
"The study", continues the note from the Rdfi, "was conducted under the same laboratory conditions of the Spallanzani Institute in Italy on comparable serum samples of individuals vaccinated with Sputnik V and Pfizer with a similar level of IgG antibodies and neutralizing activity of the virus (VNA) against the Wuhan variant ".
A NEW STRATEGY
The technical scientific team of Spallanzani, we read on Ansa , believes the results of the laboratory experiments conducted with Gamaleya "extremely encouraging to define new vaccination strategies in relation to the evolution of Covid variants".
"The joint study by the Gamaleya Center and the Spallanzani Institute confirmed the results obtained in our separate study published in December 2021. Concrete scientific data – said Gintsburg – show that Sputnik V has a greater virus neutralization activity against Omicron than to other vaccines and will play an important role in the global fight against this new contagious variant ".
THE RECALL WITH SPUTNIK LIGHT
Furthermore, according to some studies, a booster with a lighter version of the Russian vaccine (Sputnik Light) would strengthen protection against Omicron and could be administered even if different from the injections previously received.
According to the data collected, Sputnik Light would therefore be the best solution to increase the effectiveness of other vaccines and extend the protection period of the booster, avoiding boosters every 3-4 months .
WHAT THE STUDIES SAY ABOUT MIX AND MATCH WITH SPUTNIK LIGHT
On medRxiv we read that Sputnik Light, in a study conducted in Argentina, showed strong results when administered as a booster in "mix & match" studies.
The combination of Sputnik Light with vaccines produced by AstraZeneca, Sinopharm, Moderna and Cansino, conducted in 5 provinces (City and Province of Buenos Aires, as well as Córdoba, La Rioja and San Luis), showed that this lighter version of the Russian vaccine induces a stronger antibody and T cell response than two injections of the same vaccine.
Collaboration between vaccine manufacturers through the enhancement of heterologous vaccination, the experts concluded, is needed to address the rapid decline, documented in multiple studies, in the efficacy of mRna vaccines.
This is a machine translation from Italian language of a post published on Start Magazine at the URL https://www.startmag.it/sanita/quanto-il-vaccino-sputnik-v-e-efficace-contro-omicron/ on Fri, 21 Jan 2022 10:56:31 +0000.