Pfizer, Moderna and Astrazeneca: here are the new guidelines on vaccines
Recalls of Pfizer and Moderna at 42 days. Yes according to the second dose of Astrazeneca for those who have already received the first. Here's how the Italian vaccination campaign changes (and accelerates)
Recall of Pfizer and Moderna vaccines at 42 days. This is what is read in the new circular of the Ministry of Health which collects the opinion of the Technical Scientific Committee on the new guidelines for the vaccination campaign: postponing the administration of the two mRna vaccines does not invalidate the efficacy. The same circular gives the green light to the second dose of Astrazeneca for those already vaccinated.
The aim of the new rules is to speed up the vaccination campaign.
PFIZER AND MODERN: RECALL TO 42 DAYS
The recall of Pfizer and Moderna vaccines will take place at 42 days. "Even in the face of pivotal studies that indicate that the interval between the first and second dose of RNA vaccines (PfizerBioNtech and Moderna) is 21 and 28 days respectively, it is advisable to prolong the administration of the second dose in the sixth week after first dose ”, reads the circular of the Ministry of Health.
EFFECTIVENESS NOT AT RISK
The decision was made after finding that even moving the date of administration, within 42 days, does not change the effectiveness of the immune response and that "the first administration of both RNA vaccines already confers effective protection against the development of pathology COVID-19 serious in a high percentage of cases (greater than 80%) ”, explains the Ministry of Health.
OBJECTIVE: ACCELERATE VACCINATION CAMPAIGN
Moving the administration of the second has the aim, explains the same ministry, to speed up the Italian vaccination campaign. "There is still a need in the country to cover a high number of subjects at risk of developing serious or even fatal forms of COVID-19, there are conditions in which it is appropriate to give priority to public health strategies that make it possible to cover the greatest possible number of subjects in the shortest possible time ".
OK A CALL OF ASTRAZENECA
And again, again on the advice of the Scientific Technical Committee, the Ministry gives the green light to the recall with the Astrazeneca vaccine to those who have already taken the first dose.
"The information available to date on the onset of thrombosis in unusual locations (thrombosis of the cerebral venous sinuses, splanchnic thrombosis, arterial thrombosis) associated with thrombosis" testifies that these "occurred only after the first dose of the AstraZeneca vaccine, who received the first dose of this vaccine without developing this type of event, have no contraindication for a second administration of the same type of vaccine. This position could possibly be revised if different evidences emerge in the coming weeks, deriving in particular from the analysis of the safety profile of the vaccine in subjects who received the second dose in the United Kingdom ".
This is a machine translation from Italian language of a post published on Start Magazine at the URL https://www.startmag.it/sanita/pfizer-moderna-e-astrazeneca-ecco-le-nuove-linee-guida-sui-vaccini/ on Thu, 06 May 2021 04:10:18 +0000.